Pat Sandra | Authors

Separation Science: The State of the Art: On the Contemporary Analysis of Protein Biopharmaceuticals

In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, key opinion leaders from the separation science community explore contemporary trends in separation science and identify possible future developments.

Separation Science: The State of the Art: How Mature is Gas Chromatography? An Industry Perspective

In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, key opinion leaders from the separation science community explore contemporary trends in separation science and identify possible future developments.

Minimizing the Risk of Missing Critical Sample Information by Using 2D-LC

This article explores potential pitfalls associated with 1D‑LC and how 2D‑LC can overcome these obstacles.

Minimizing the Risk of Missing Critical Sample Information by Using Two-Dimensional Liquid Chromatography

Online 2D-LC is a powerful—and accessible—tool for analyzing pharmaceutical and biopharmaceutical samples, in both R&D and QC. It’s now easier than ever to develop 2D-LC methods, and they can be run in a fully automated manner.

Diving into the Structural Details of In Vitro Transcribed mRNA Using Liquid Chromatography–Mass Spectrometry-Based Oligonucleotide Profiling

An overview of mRNA-based vaccine production and a discussion on the methods that are currently in use to check the quality of these vaccines.

High Analytical Performance for Untargeted Aroma Profiling by Combining Dynamic Headspace Sampling, Capillary Gas Chromatography and Time‐of‐Flight Mass Spectrometry

This article looks at the benefits of combining dynamic headspace sampling (DHS) with capillary GC–TOF-MS as a tool for untargeted analysis of aroma compounds in food and beverages. Applications for the analysis of strawberry yoghurt, chocolate, and red wine are described.