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Frank David | Authors
Articles
Polysorbate Analysis in Biopharmaceutical Applications—A Snapshot of the Analytical Toolbox
An overview of different approaches for the qualitative and quantitative analysis of polysorbates.
Separation Science: The State of the Art: How Mature is Gas Chromatography? An Industry Perspective
In this extended special feature to celebrate the 35th anniversary edition of LCGC Europe, key opinion leaders from the separation science community explore contemporary trends in separation science and identify possible future developments.
Analysis of Ethylene Oxide and 2-Chloroethanol in Food Products: Challenges and Solutions
The importance of accurate analysis methods for EtO and 2-CE in food is essential and the demand for robust methods that are able to deliver high sample throughput with minimal instrumental downtime is high.
High Analytical Performance for Untargeted Aroma Profiling by Combining Dynamic Headspace Sampling, Capillary Gas Chromatography and Time‐of‐Flight Mass Spectrometry
This article looks at the benefits of combining dynamic headspace sampling (DHS) with capillary GC–TOF-MS as a tool for untargeted analysis of aroma compounds in food and beverages. Applications for the analysis of strawberry yoghurt, chocolate, and red wine are described.
GC: The State of the Art
In this extended special feature to celebrate the 30th anniversary edition of LCGC Europe, leading figures from the separation science community explore contemporary trends in separation science and identify possible future developments. We asked key opinion leaders in the field to discuss the current state of the art in gas chromatography instruments.
On-Line Two-Dimensional Liquid Chromatography (2D-LC) for the Analysis of Pharmaceuticals
On-line two-dimensional liquid chromatography (2D-LC) embracing mainly comprehensive LC (LC×LC) and multiple heart-cutting LC (mLC–LC) offers new opportunities for in-depth characterization of pharmaceuticals. Reversed-phase LC × reversed-phase LC using different column chemistries and mobile phases provides good orthogonality for a wide range of applications related to small molecule drugs. Moreover, hardware configurations and software are now commercially available to perform LC×LC and mLC–LC measurements in a reproducible manner.