Special Issues-10-02-2013

The experimental design that considers gradient time and temperature was expanded to include a third factor, either pH or ternary composition, and modelling software facilitated the analysis.

The parameters that should be considered in the optimization of HPLC methods are explained and then illustrated through the analysis of two commercial agricultural products.

Supercritical fluid chromatography has become a viable option for the separation scientist in diverse areas, and the field now seems more adequately described as an extension of HPLC, or perhaps as "carbon dioxide–based HPLC".

The authors explain modern UHPLC instrument design and outline simple procedures to identify causes of poor column and method performance.

When choosing the articles to include in this supplement, my selection was based on a very simple criterion.

Click the title above to open the LCGC Europe October 2013 Recent Developments in HPLC and UHPLC Supplement, Vol 26 No s10, in an interactive PDF format.