Acetonitrile Shortage and UHPLC

February 2, 2009

The current acetonitrile shortage is an important factor in pushing analysts in the pharmaceutical, food, environmental, and chemical industries toward considering the use of ultrahigh?pressure liquid chromatography (UHPLC) as a means to save solvent.

The current acetonitrile shortage is an important factor in pushing analysts in the pharmaceutical, food, environmental, and chemical industries toward considering the use of ultrahigh–pressure liquid chromatography (UHPLC) as a means to save solvent. According to Waters Corporation, replacing a traditional high performance liquid chromatography (HPLC) system with a UHPLC system such as the company’s ACQUITY UltraPerformance LC system can reduce acetonitrile consumption by at least 70% without affecting productivity or performance.