Acetonitrile Shortage and UHPLC
The current acetonitrile shortage is an important factor in pushing analysts in the pharmaceutical, food, environmental, and chemical industries toward considering the use of ultrahigh?pressure liquid chromatography (UHPLC) as a means to save solvent.
The current acetonitrile shortage is an important factor in pushing analysts in the pharmaceutical, food, environmental, and chemical industries toward considering the use of ultrahigh–pressure liquid chromatography (UHPLC) as a means to save solvent. According to Waters Corporation, replacing a traditional high performance liquid chromatography (HPLC) system with a UHPLC system such as the company’s ACQUITY UltraPerformance LC system can reduce acetonitrile consumption by at least 70% without affecting productivity or performance.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
