Advantages of Using Ultra High Temperature in High Throughput LC and LC–MS
This work demonstrates gains of up to 7-fold in signal to noise ratio with APCI mass spectrometry and reduction in analysis times of 5- to 8-fold
The use of very high temperatures (up to 200 °C) in liquid chromatography has advantages in terms of throughput and sensitivity of the analysis. The work presented in this article demonstrates gains of up to 7-fold in signal-to-noise ratios with APCI mass spectrometry and reduction in analysis times of 5- to 8-fold.
LC–MS/MS-Based System Used to Profile Ceramide Reactions to Diseases
April 26th 2024Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
Traditional Chinese Medicine’s Effects on Liver Cancer Measured Using New UHPLC–QTOF-MS System
April 22nd 2024Scientists from Anhui University of Chinese Medicine in Hefei, China recently investigated the mechanisms behind what makes huachansu tablets, a type of traditional Chinese medicine (TCM), effective against liver cancer.
