Advantages of Using Ultra High Temperature in High Throughput LC and LC–MS

The use of very high temperatures (up to 200 °C) in liquid chromatography has advantages in terms of throughput and sensitivity of the analysis. The work presented in this article demonstrates gains of up to 7-fold in signal-to-noise ratios with APCI mass spectrometry and reduction in analysis times of 5- to 8-fold.

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