Double your discovery: The Agilent 1260 Infinity Hybrid SFC/UHPLC System packs two orthogonal separation modes into one instrument, bringing you more information from a single automated sequence.
The new Agilent 1260 Infinity Hybrid SFC/UHPLC System packs two orthogonal separation modes into one instrument, bringing you more information from a single automated sequence. Switching between the two techniques SFC and UHPLC has never been so easy. A software-controlled valve allows you to alternate smoothly and reproducibly between SFC and UHPLC methods within a single analysis sequence – no hardware changes are needed and equilibration times are minimal.
The Agilent 1260 Infinity Hybrid SFC/UHPLC system is the only SFC system available that offers true UHPLC capability with a 600 bar power range. It also provides the broadest price/performance range of any SFC system available. Whether you want to upgrade your current Agilent 1100 or 1200 Series system, or start with the Agilent 1260 Infinity Analytical SFC system as a dedicated instrument, you can easily adapt your system to create a hybrid unit and then further expand your detection capabilities with an Agilent evaporative light scattering detector or a mass spectrometer from Agilent’s extensive LC/MS portfolio.
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The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Using Chromatography to Explore Fluorescent Bioactive Compounds in the Coelomic Fluid of Earthworms
February 6th 2025A study aiming to identify fluorescent bioactive compounds in the coelomic fluid of earthworms, as well as to investigate their structural and functional characteristics for possible use in biomedical applications, utilized a variety of chromatographic techniques.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.