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Analysis of Formoterol, Budesonide, and Related Compounds by UPLC–MS

October 4, 2019
By Waters Corporation
Article

Sponsored Content - EU

Explore the analytical potential of the AQbD approach for achieving high-performance separations of formoterol, budesonide, and its related compounds.

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Monoclonal antibodies (mAbs) are effective therapeutics for cancers, auto-immune diseases, viral infections, and other diseases. Recent developments in antibody therapeutics aim to add more specific binding regions (bi- and multi-specificity) to increase their effectiveness and/or to downsize the molecule to the specific binding regions (for example, scFv or Fab fragment) to achieve better penetration of the tissue. As the molecule gets more complex, the possible high and low molecular weight (H/LMW) impurities become more complex, too. In order to accurately analyze the various species, more advanced detection than ultraviolet (UV) is required to characterize a mAb sample.


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AAV Application Notebook: Characterizing AAVs with Light Scattering

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Wyatt’s instruments and techniques constitute platform methods for effective product and process development, as well as quality control, of AAVs for gene therapy.


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USP-Compliant HPLC Analysis of Lamotrigine

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Efficient and accurate HPLC analysis of lamotrigine in compliance with USP


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HPLC Analysis of Hydrocortisone in Accordance with the United States Pharmacopeia

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USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System


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USP-Compliant HPLC Analysis of Pregabalin

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Efficient and compliant HPLC analysis of pregabalin


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VOC Metabolites in Urine by HPLC with UV Detection

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A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

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SEC-MALS of Antibody Therapeutics—A Robust Method for In-Depth Sample Characterization

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Tosoh Bioscience
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Article

Monoclonal antibodies (mAbs) are effective therapeutics for cancers, auto-immune diseases, viral infections, and other diseases. Recent developments in antibody therapeutics aim to add more specific binding regions (bi- and multi-specificity) to increase their effectiveness and/or to downsize the molecule to the specific binding regions (for example, scFv or Fab fragment) to achieve better penetration of the tissue. As the molecule gets more complex, the possible high and low molecular weight (H/LMW) impurities become more complex, too. In order to accurately analyze the various species, more advanced detection than ultraviolet (UV) is required to characterize a mAb sample.


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AAV Application Notebook: Characterizing AAVs with Light Scattering

Wyatt Technology Corporation
May 12th 2022
Article

Wyatt’s instruments and techniques constitute platform methods for effective product and process development, as well as quality control, of AAVs for gene therapy.


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USP-Compliant HPLC Analysis of Lamotrigine

PerkinElmer, Inc.
April 26th 2022
Article

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP


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HPLC Analysis of Hydrocortisone in Accordance with the United States Pharmacopeia

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A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

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