Wyatt Technology Corporation | Authors

SEC-MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage.

Field-flow fractionation coupled to multi-angle light scattering (FFF-MALS) is a powerful analytical tool that determines multiple CQAs of LNP-RNA nanoparticles.

SEC with multi-angle light scattering (SEC-MALS) or in conjunction with a viscometer (SEC-MALS-IV) effectively characterizes branching in polymers.

SEC–MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage conditions.

Wyatt’s instruments and techniques constitute platform methods for effective product and process development, as well as quality control of AAVs for gene therapy.

Light scattering facilitates vaccine development by enabling the analysis of size, shape, molar mass, and other parameters derived from these properties.