Wyatt Technology Corporation

Webinar Date/Time: Thu, Sep 5, 2024 11:00 AM EDT

Determine the molecular weight of low abundant species with confident with the highly sensitive DAWN MALS detector and improved peak separation with Waters BEH Column.

Explore SEC-MALS-RI multi-attribute quantification of antibodies, biosimilars, and AAVs.

Explore the optimization of AAV separation and the combined intrinsic fluorescence detection with SEC-MALS for low-concentration measurement.

Webinar Date/Time: Wed, Nov 1, 2023 11:00 AM EDT

SEC-MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage.

Field-flow fractionation coupled to multi-angle light scattering (FFF-MALS) is a powerful analytical tool that determines multiple CQAs of LNP-RNA nanoparticles.

SEC with multi-angle light scattering (SEC-MALS) or in conjunction with a viscometer (SEC-MALS-IV) effectively characterizes branching in polymers.

SEC–MALS quantifies biophysical attributes of mRNA, including molar mass, percent aggregates, Rg, and Rh, and how they are affected by formulation and storage conditions.

Wyatt’s instruments and techniques constitute platform methods for effective product and process development, as well as quality control of AAVs for gene therapy.

Light scattering facilitates vaccine development by enabling the analysis of size, shape, molar mass, and other parameters derived from these properties.

SEC-MALS is a platform method for effective product and process development, as well as quality control, of AAVs for gene therapy.

SEC–MALS characterizes PEGylated proteins to determine the protein-PEG ratio and the molar masses of the constituent protein and PEG at each eluting fraction.

SEC-MALS and CG-MALS characterize viral glycoprotein (vGP) self-association and the absolute stoichiometry and affinity of vGP: antibody interactions.

This note demonstrates the use of DLS and online multi-angle light scattering with field-flow fractionation (FFF-MALS) for characterizing retroviral viral vectors.

Field-flow fractionation with multi-angle and dynamic light scattering (FFF–MALS–DLS) combines size-based separation with absolute size and structure determination.

Light scattering quantifies key attributes of lipid nanoparticle gene vectors such as payload, size, titer, and stability in formulation and physiological media.

Tue, Aug 23, 2022 11:00 AM EDT Advanced PAT tools such as RT–MALS offer in-depth characterization of biological molecules and nanoparticles to help optimize manufacturing processes.

Light scattering methods inform on essential properties and attributes of vaccines including size, aggregation, stability, interactions, composition, and conformation.

Large viral vectors are characterized rapidly using dynamic light scattering and in-depth by multi-angle light scattering in combination with field-flow fractionation.

Quality attributes of Adeno-Associated Virus (AAV) vectors are achieved with multi-angle light scattering coupled to separation methods and high-throughput dynamic light scattering.

SEC-MALS quantifies biophysical attributes of mRNA including molar mass, percent aggregates, Rg and Rh, and how they are affected by formulation and storage conditions.

This white paper presents the characterization of protein-DNA complexes using two complementary multi-angle light scattering techniques, SEC-MALS and CG-MALS.

IEX-MALS overcomes some of the restrictions of SEC-MALS that arise from SEC, while providing absolute molar mass, size, and quality assessment of heterogeneous proteins.

This note demonstrates the use of DLS and online multi-angle light scattering with field-flow fractionation (FFF-MALS) for characterizing retrovial viral vectors.

SEC-MALS identifies monomers, dimers, hexamers, and higher aggregates of insulin to determine optimal formulation, storage, and administration conditions.

Wyatt’s instruments and techniques constitute platform methods for effective product and process development, as well as quality control, of AAVs for gene therapy.

Branching analysis of amylopectin requires a linear amylose analog. Synthetic amylose was prepared and characterized by SEC-MALS to determine if branching is present.

Field-flow fractionation with online static and dynamic light scattering constitutes a powerful and versatile system for nano-pharmaceutical characterization.

February 24th, 2022, at 8am PST | 11am EST | 4pm GMT | 5pm CET Join us for this informative webcast to learn how to illuminate block copolymers with SEC-MALS.