CE-MS and Coronary Artery Disease Diagnosis
Researchers from Germany, Belgium, the UK, and Australia conducted a study of urine from patients with and without coronary artery disease to look for proteome patterns indicative of the disease.
Researchers from Germany, Belgium, the UK, and Australia conducted a study of urine from patients with and without coronary artery disease to look for proteome patterns indicative of the disease. They used capillary electrophoresis coupled with mass spectrometry (CE–MS) to analyze the urine samples. They examined a combination of 17 polypeptides and found specific polypeptide patterns in the urine that were associated with coronary artery disease in patients with angina. They suggest that further studies are necessary to evaluate the clinical value of the CE–MS urine proteome analysis for diagnosis of coronary artery disease.
LC–MS/MS-Based System Used to Profile Ceramide Reactions to Diseases
April 26th 2024Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
