Direct MS Simplifies Analysis of Challenging Compounds

July 13, 2020

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The analysis of some volatiles is a real challenge for conventional GC and LC methods. Direct mass spectrometry-specifically, selected ion flow tube mass spectrometry (SIFT-MS)-can address these analytes in a streamlined manner for routine analysis. Join us for this webcast to learn more, with examples of the analysis of formaldehyde, volatile fatty acids, hydrogen sulfide and organosulfur compounds, ammonia and amines, nitrosamines, and siloxanes. Live: Monday, Jul. 13, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after airing until Jul. 13, 2021 Register free

Register free: http://www.chromatographyonline.com/lcgc_w/streamline_routine_volatiles_analysis_series

Event Overview:

Part 4 of a 4 Part Series: Streamline Routine Volatiles Analysis-Filling the Awkward Gap Between GC and LC

Direct mass spectrometry (direct MS) facilitates faster method development and validation, plus it provides high throughput for routine analysis. But the benefit of adoption of selected ion flow tube mass spectrometry (SIFT-MS)-the leading automated direct mass spectrometry technique for analysis of volatile compounds-also has an additional benefit: greatly simplifying the analysis of important chromatographically challenging volatiles, such as formaldehyde, volatile fatty acids, organosulfur compounds (and hydrogen sulfide), and amines (and ammonia). Straightforward analysis without requiring derivatization, drying steps, or selection of special columns, detectors, or analysis conditions is a direct result of the soft chemical ionization used in SIFT-MS. 

This final webcast (of a series of four) on routine SIFT-MS analysis focuses on case studies that demonstrate simple analysis of chromatographically volatile compounds. Formaldehyde receives special attention as it is of important across a wide range of industries (from environmental to pharmaceutical testing) and its case study also includes validation of an unconventional analytical method in compliance with ICH Q2(R1) Guidelines for regulatory submission.

Key Learning Objectives:

  • Very brief introduction to SIFT-MS and its automation for those who missed Parts 1 to 3

  • Why some volatiles are a real challenge for conventional lab methods

  • Case studies illustrating how SIFT-MS overcomes these challenges, covering formaldehyde, volatile fatty acids, hydrogen sulfide and organosulfur compounds, ammonia and amines, nitrosamines, and siloxanes

Speakers: Mark Perkins, PhD, Senior Applications Chemist, Anatune Limited, United Kingdom

Vaughan Langford, PhD, Principal Scientist, Syft Technologies, New Zealand

Time and date: Monday, Jul. 13, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST

On demand available after airing until Jul. 13, 2021.

Sponsor: Syft Technologies Inc.

Register free: http://www.chromatographyonline.com/lcgc_w/streamline_routine_volatiles_analysis_series

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