GPC/SEC Adventures in (Bio)Polymer Analysis

An LC×LC–HRMS method was developed for the characterization of phenolic compounds in cannabis, with flavoalkaloids identified for the first time.

In episode #37 of Analytically Speaking, podcast host Dr. Jerry Workman speaks with Dr. Austin Daniels, application scientist for Yokogawa Fluid Imaging Technologies, about flow imaging microscopy (FIM), a new technology for sub-visible particle characterization in biologics.

A study conducted by the College of Veterinary Medicine of Midwestern University (Glendale, Arizona), the University of California Davis School of Veterinary Medicine (Davis, California) and the College of Veterinary Medicine of the University of Tennessee (Knoxville, Tennessee) set out to describe the pharmacokinetics of oral gabapentin (GABA) in goats given as a single dose (SD) and multidose (MD) regimen, as well as to document any adverse effects after administration. Plasma samples were collected and analyzed via reversed-phase high performance liquid chromatography (RP-HPLC).

An innovative workflow that combines iterative data-dependent acquisition (DDA) and data-independent acquisition (DIA) to enhance the identification of unknown pollutants in urban runoff is presented.