Gas chromatography (GC) tests show spoilage yeasts alter flavor and raise alcohol in NoLo beer.
|Articles|August 3, 2015
HRMS in Clinical Research from Targeted Quantitation to Metabolomics
Author(s)Thermo Fisher Scientific
In this webinar, we will discuss the use of new, affordable HRMS instruments in quantitative clinical research analyses, demonstrating the sensitivity and selectivity of these instruments for this work. Examples of clinical research quantification work in HR full scan or MS-MS mode will be presented and compared with results from triple-quadrupole-MS. We will also discuss an example of Qual/Quan analysis in a study of the fate of an anti-cancer agent in humans, where over 40 metabolites were identified and quantified. We will also show metabolomics data underscoring the versatility of HRMS instruments.
Advertisement
Advertisement
Related to this article
Liquid chromatography–tandem mass spectrometry (LC–MS/MS) finds low glyphosate residues of the weedkiller glyphosate in coffee beans.
This week, Chromatography Online explored how the technique is advancing wastewater drug monitoring, siRNA method development, and food safety testing, with previews of RAFA 2026 and a return to HPLC fundamentals with Michael Dong.
Recent EU legislation on PFAS shifts from monitoring individual compounds toward managing them as a chemical class.
In this seventh part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why 2.1-mm i.d. columns are less preferred for pharmaceutical quality control.
Ultrahigh-performance liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF-MS) shows how soaking and cooking break down soybean fats.
Liquid chromatography–tandem mass spectrometry (LC–MS/MS) links altered metabolism to lingering symptoms in Ebola survivors.
Nicolai Zederkopff explores chromatography’s role to help implement the maximum tolerable level (MTL) framework for food adulteration to translate analytical results into compliance decisions.
Advertisement
Advertisement
Trending on LCGC International
1
Conversations with Michael Dong: Why 2.1-mm i.d. Columns Are Preferred for Pharmaceutical Quality Control
2
Conversations with Michael Dong: Acetonitrile and Methanol: A Comparison of Their Chromatographic Properties
3
Mass Spectrometry Imaging in Food: The Power and the Limits
4
UHPLC-HRMS Screens Alkaloids in Cereals and Spices
5