This application note demonstrates robust and sensitive quantitation of 10 nitrosamines, and the use of the LC–SRM–MS to quantify nitrosamine impurities in metformin.
Progress with Alternative Solvents for SIFT-MS: 2024 Update
January 30th 2025Explore advancements in utilizing alternative solvents for SIFT-MS. This tech note introduces three new solvents—acetonitrile, N,N'-dimethylpropyleneurea (DMPU), and propylene glycol (PG)—and highlights the enhanced sensitivity and applications of existing solvents like triacetin. The findings demonstrate significant benefits in analyzing diverse VOCs while addressing challenges in method development.