News|Podcasts|August 16, 2024
Modern HPLC Strategies: Improving Retention and Peak Shape for Basic Analytes
Author(s)AMT
In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.
Advertisement
Newsletter
Join the global community of analytical scientists who trust LCGC for insights on the latest techniques, trends, and expert solutions in chromatography.
Advertisement
Advertisement
Advertisement
Trending on LCGC International
1
LC–MS/MS and ICP-MS Characterization of Toxic Elements and Organic Contaminants in Tattoo Inks
2
Rapid Native HIC–MS Using Ammonium Tartrate for Robust Drug-to-Antibody Ratio Characterization of Antibody–Drug Conjugates
3
DoE-Optimized GC–FID Method for Robust Terpene Profiling in Essential Oils
4
Best of the Week: Profiling Endogenous Protein Complexes, Previewing Riva 2026
5