The recent introduction of high resolution, accurate mass (HRAM) OrbitrapTM technology coupled to GC brings a new level of performance and flexibility in full scan acquisition and more. Comparable sensitivity and selectivity of triple quadrupole GC-MS/MS, but with broad scope, and the capability for simultaneous targeted and non-targeted analysis of pesticides at low ng/g concentrations, in complex sample types. In this Q & A, Paul Silcock discusses the story so far, around the use of Orbitrap GC-MS for quantitative and qualitative multi-residue analysis of pesticides.
Kirstine Nielsen of Aarhus University (Denmark) discusses how targeted metabolomics ratios helped build a robust bloodstain time-since-deposition tool.
Gérard Hopfgartner explains how atmospheric pressure photoionization can generate radical cations in LC–MS, unlocking EI-style spectra and NIST's spectral library.
LCGC International spoke to Akina Nara of Japan’s Tohoku Medical and Pharmaceutical University about a new study which links a blood compound to how long a body has been dead.
A method coupling gas chromatography-tandem mass spectrometry (GC-MS/MS) and multiple reaction monitoring (MRM) tracks lipid markers of decomposition in commingled remains.
This week's top stories on the Chromatography Online website spotlight LCGC International's new SFC-focused interview series charting the technique's rise alongside LC and GC, complemented by a practical GC data-reporting refresher and a study using chromatography to detect trace pesticides in tap water.