Optimizing Chromatographic Conditions for Protein Analysis with theACQUITY UPLC H-Class Bio System
Presented By
Across the pharmaceutical industry, there is growing emphasis on the development of biopharmaceuticals as the next wave of drugs contributing to human health. In this podcast series, we’ll be discussing how chromatographic analyses of biopharmaceuticals, particularly proteins, compare to the more familiar assays of small molecule drugs and the benefits that UPLC® Technology can offer. The types of assays will be described and the basis for choosing them is considered. We’ll also discuss recent developments in ways to improve an analytical method.
Biopharmaceutical proteins are often best analyzed using ion exchange chromatography. Optimization of these methods has become much more efficient with UPLC technology. In this episode, the steps and considerations required for developing an ion exchange method for protein analysis are discussed.
Add this Podcast feed to your media player
Interpreting Metabolites and Biosynthetic Pathways of Musk with GC–MS
May 22nd 2025Gas chromatography–mass spectrometry (GC–MS) was used to detect the chemical components of natural musk, harvested from forest musk deer at multiple stages of maturity. This research combines metabolomic profiling with biosynthetic pathway analysis to identify potential precursors and enzymes involved in musk biosynthesis.
HPLC 2025 Preview: HPLC 2025 Hits Bruges
May 22nd 2025The 54th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2025) will be held from Sunday through Thursday, June 15–19 2025, in Bruges, Belgium. LCGC International spoke to the Scientific Committee to find out what’s in store.
Quantifying Isavuconazole in Dried Blood Spots Using HPLC
May 21st 2025Isavuconazole, an antimycotic agent used to treat fungal infections, can typically be found during dried blood spot sampling. However, there are obstacles that keep it from being an ideal approach for properly determining the drug’s presence.