Researchers Analyze Complex Sugar Molecule Using LC-MS

August 10, 2007

A Team of Scientists from MIT have developed a method for unveiling the genetic code of heparan sulfate (a sugar molecule found on the surface of all cells in the body) and heparin (a commercial drug used to stop clotting).

A Team of Scientists from MIT have developed a method for unveiling the genetic code of heparan sulfate (a sugar molecule found on the surface of all cells in the body) and heparin (a commercial drug used to stop clotting).
For years, researchers have been able to determine the genetic codes of protein and DNA, however, doing the same for sugars has proven to be troublesome because of the complexity of these molecules.
Led byMIT Professor of Biology Robert D. Rosenberg and postdoctoral associates Kuberan Balagurunathan and Zhengliang L. Wu, technical associate Miroslaw Lech, research affiliate Lijuan Zhang, and research scientist David Beeler, the technique developed by the group uses LC-MS.

To view, please visit: http://web.mit.edu/newsoffice/nr/2002/sugar2.html

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