SEC Analysis of Star Branched Polyethylene Glycol without Column Interaction

Recent advances in polymer chemistry have led to the development of novel materials with both controlled functionality and structure resulting in unusual rheological properties. Examples include the many di- and triblock copolymer architectures and dendritic systems. These materials often include regions of different polarity and hydrophobicity and therefore represent a challenge to the analytical chemist. This application note illustrates the analysis of a star-branched polyethylene glycol with a significant hydrophobic component by aqueous SEC.