To Selectivity and Beyond: Celebrating 18 Years of the Hydrophobic Subtraction Model

In this Thursday morning session, the latest applications of the hydrophobic subtraction model (HSM) will be presented. The session will be held in Room W181A, and begins at 8:30 am.

Dwight Stoll of Gustavus Adolphus College, will kick off the session at 8:30 am with a talk on  the use of the HSM to identify columns that are very similar to or different from each other, and the development of a free public database of reversed-phase liquid chromatography (LC) columns.

Next, Richard Henry, an independent consultant, will discuss the use of the HMS to developrugged USP HPLC methods. His talk starts at 9:10 am.

Retention prediction in revesed-phase LC using quantitative structure-retention relationships using the HSM will be presented next, by John Dolan of LC Resources. This talk begins at 9:45 am.

After the recess, Tony Taylor of Crawford Scientific will discuss “Refining the Hydrophobic Subtraction Model using Mathematical Modelling of a Large Data set to Improve LC Column Comparison.” The discussion starts at 10:35 am.

Joe Foley of Drexel University will present the final talk in this session entitled “Are Two Columns Better than One?: Answers from the Hydrophobic Subtraction Model Database and Other Sources.” This talk will be under way at 11:10 am and conclude at 11:45 am.