Metrohm Application Note
Reversed-Phases for LC Deliberately Doped with Positive Charge: Tips and Tricks for Effective Use
May 13th 2025In this month's edition of LC Troubleshooting, Dwight Stoll and his fellow researchers discuss both the benefits (improved peak shape/loading) and challenges (excessive interaction) associated with charge-doped reversed-phase (RP) columns for both analytical and preparative separations.
Evaluating the Accuracy of Mass Spectrometry Spectral Databases
May 12th 2025Mass spectrometry (MS) can be effective in identifying unknown compounds, though this can be complicated if spectra is outside of known databases. Researchers aimed to test MS databases using electron–ionization (EI)–MS.
Detecting Hyper-Fast Chromatographic Peaks Using Ion Mobility Spectrometry
May 6th 2025Ion mobility spectrometers can detect trace compounds quickly, though they can face various issues with detecting certain peaks. University of Hannover scientists created a new system for resolving hyper-fast gas chromatography (GC) peaks.