When working with milk as a matrix, Strata-X PRO SPE removes phospholipids more efficiently than traditional SPE to reduce any ion suppression that may occur during LC-MS/MS analysis.
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.