UHPLC Method Development and Modelling in the Framework of Quality by Design

The DEGASi range of inline degassers from Biotech Fluidics employ a Systec AF gas permeable membrane with a constant vacuum degassing system.

Photodegradation of plastic products is known to accelerate weathering and the resulting release of chemical additives and particles to the environment, however these processes are complex. Here, eight different plastic consumer products were leached in double-distilled water under exposure to strong ultraviolet (UV) light for ten days, and the chemical composition of the leachates was compared to their respective dark controls. The leachates and plastic particles were investigated with a wide battery of chemical-analytical tools to broadly characterize the underlying processes and possible hazards. These covered (a) metal(loid) analysis, (b) microplastic analysis, (c) analysis of >70 organic target analytes and (d) nontargeted screening of the extracts.

The serum/plasma estradiol is useful for diagnosis, pathology, and therapeutic efficacy monitoring of estrogen-dependent diseases, according to the authors.

We present a reliable NanoPak-C All Carbon SPE method for extracting and detecting 15 OCPs from small quantities of soil (100 mg) and river water (200 µL) samples.