Ultra Performance Liquid Chromatography Coupled to Orthogonal Quadrupole TOF–MS(MS) for Coupled Metabolite Identification

Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.

Biozen dSEC-7 accurately resolves AAV serotypes 5, 8 and 9 monomer from aggregates in under 10 minutes with consistent results across different mobile phase conditions.

LCGC International sat down with Jeff Zonderman, senior vice president of Bruker Applied MS at Analytica, to discuss sustainability, PFAS analysis, and the company’s year-old mass spectrometry division.

The serum/plasma estradiol is useful for diagnosis, pathology, and therapeutic efficacy monitoring of estrogen-dependent diseases, according to the authors.