Gas chromatography–mass spectrometry (GC–MS) and ion chromatography profile wasabi and mustard heat and acidity.
|Articles|July 18, 2012
- The Column-07-18-2012
- Volume 8
- Issue 13
Understanding the Behaviour of Pharmaceutical Polymers
Author(s)Greg D. Saunders
This article discusses GPC and gives examples of the use of the technique in excipient analysis.
New philosophies in pharmaceutical industry such as Quality by Design (QbD) require a detailed understanding of the properties and behaviour of drug components, including polymeric excipients such as binders and disintegrants. Gel permeation chromatography (GPC, also known as size exclusion chromatography) is a vital tool for investigating the behaviour of polymers, and is increasingly employed in pharmaceutical laboratories to investigate macromolecules. This article discusses GPC and gives examples of the use of the technique in excipient analysis.
Articles in this issue
over 14 years ago
Prehistoric dairy farmingover 14 years ago
Back To Basicsover 14 years ago
Live Lab tour reviewover 14 years ago
Alternatives to Silicone Breast Implantsover 14 years ago
Supplement analysisover 14 years ago
Innovation centre opensRelated to this article
How feasible is it to integrate this Bayesian graph-theory methodology into existing commercial chromatography software workflows for semi-automated data curation in routine analytical laboratories?
Reversed-phase high-performance liquid chromatography (RP-HPLC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) show frequent milking alters cobra venom toxin makeup.
Gabriel Vivó-Truyols outlines the benefits and challenges of combining graph theory with Bayesian statistics to automate peak assignment and alignment.
This week, Chromatography Online’s coverage spanned lipidomics-based early cancer detection, career paths in separation science, machine learning and uncertainty-driven approaches to LC method development, new EU wastewater rules for pharmaceutical micropollutants, automated Separation Quality Factor (SQF) evaluation in chromatography data systems, and solutions to GLP-1 peptide analysis challenges.
Gabriel Vivó-Truyols from the Spanish Council for Scientific Research, Madrid, Spain. discusses his work on using graph theory and Bayesian statistics for peak assignment and chromatographic alignment.
Gas chromatography (GC) analysis ties prenatal mindfulness to shifts in placental fatty acids.
Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography-quadrupole time-of-flight mass spectrometry (LC–qTOF–MS) reveal metabolic shifts in tricuspid regurgitation.
Trending on LCGC International
1
GLP-1 Peptide Analysis: Challenges and Solutions
2
HPLC–DAD Method Tracks Semaglutide and Tirzepatide Stability
3
Industry Roundup: Waters Posts Strong Third Quarter as LC–MS and Chromatography Consumables Drive Growth, Acquires Ion Mobility Pioneer MOBILion
4
LC–MS/MS Dried Blood Spot Test for Galactosemia
5