|Articles|May 2, 2004

The Application Notebook

  • The Application Notebook-05-01-2004
  • Volume 0
  • Issue 0

Unimolecular Low-Bleed Phases

GC column bleed has been postulated to be caused by "backbiting" of the siloxane chain and volatility of noncrosslinked oligimers...


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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.