Validating a Reversed-Phase HPLC Method to Determine Residual Nonoxynol-9 on Pharmaceutical Process Equipment Using a Nonporous Silica Column

Mark Shapiro;Ross DeNisco;Michael J. Shifflet;Cora Levin;

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Validating a Reversed-Phase HPLC Method to Determine Residual Nonoxynol-9 on Pharmaceutical Process Equipment Using a Nonporous Silica Column

Published on: March 1, 2001

Mark Shapiro, Ross DeNisco, Michael J. Shifflet, Cora Levin

LCGC North America

LCGC North America, LCGC North America-03-01-2001, Volume 19, Issue 3

The authors' laboratory developed and validated an HPLC method to test for residual nonoxynol-9 on stainless steel, PTFE, and acrylic substrates.