Validating a Reversed-Phase HPLC Method to Determine Residual Nonoxynol-9 on Pharmaceutical Process Equipment Using a Nonporous Silica Column

March 1, 2001
Mark Shapiro

,
Ross DeNisco

,
Michael J. Shifflet

,
Cora Levin

LCGC North America

Volume 19, Issue 3

The authors' laboratory developed and validated an HPLC method to test for residual nonoxynol-9 on stainless steel, PTFE, and acrylic substrates.