Validating a Reversed-Phase HPLC Method to Determine Residual Nonoxynol-9 on Pharmaceutical Process Equipment Using a Nonporous Silica Column

March 1, 2001
Mark Shapiro

Ross DeNisco

Michael J. Shifflet

Cora Levin

LCGC North America

LCGC North America, LCGC North America-03-01-2001, Volume 19, Issue 3

The authors' laboratory developed and validated an HPLC method to test for residual nonoxynol-9 on stainless steel, PTFE, and acrylic substrates.