Vol 17 No 1 The Column January 2021 North American PDF
Click the link below to open The Column January 2021 North American issue, Volume 17, Number 1, in an interactive PDF format.
Evaluating Antimicrobial Potential of Articaine Derivatives in Oral Infections with CMC
May 20th 2025Cell membrane chromatography (CMC) technology was used by researchers in screening efficacy and antibacterial ability of articaine (AT) derivatives in the pre-emptive treatment of oral infections.
Hydrophilic Interaction Chromatography (HILIC) and Direct Online Disruption of Lipid Nanoparticles
May 19th 2025Two proof-of-concept hydrophilic interaction chromatography HILIC) methods were developed in a joint study conducted by the University of Geneva (Switzerland), Sanofi, and the Waters Corporation—one for disrupting LNPs and retaining the mRNA, and another for detecting only unencapsulated mRNA to assess encapsulation efficiency. LCGC International spoke to Jonathan Maurer, first author of the paper that resulted from this study, about the methods and the efforts that led up to their development.
This article discusses how integrating seven prioritization strategies can enhance compound identification, support environmental risk assessment, and accelerate decision-making.
