News|Articles|September 24, 2026

Where LC-MS/MS Meets the ER Clock: The Case for Paper Spray-MS in Acute Drug Toxicity Screening

Paper spray-mass spectrometry vs. liquid chromtography-tandem mass spectrometry (LC-MS/MS): Can rapid screening rival the gold standard in ER drug testing?

For forensic and clinical toxicologists, the gold-standard analytical technique is not always the one you can use when it matters most.

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LC-MS/MS Method Detects Propofol via Metabolite
Koji Yamaguchi of the International University of Health and Welfare (Narita, Japan) discusses a novel derivatized liquid chromatography-tandem mass spectrometry (LC-MS/MS) method plus propofol glucuronide (PRG) marker which improves forensic propofol detection.