Attila Felinger | Authors

Attila Felinger is a Professor of Analytical Chemistry at the University of Pécs in Hungary. He is the head of the Analytical and Environmental Chemistry Department at the Faculty of Sciences, and he is at the helm of the Institute of Bioanalysis at the Medical School (both at the University of Pécs). In addition, he serves as President of the Hungarian Society for Separation Sciences. His research interests focus on the fundamentals of chromatography including preparative and analytical separations, as well as the chemometric analysis of analytical measurements.


The Impact of Column Hardware on Efficiency in Liquid Chromatography (LC)

Column hardware in liquid chromatography—that is, the tubing, the frits, and fitting—has a strong influence on separation performance or the reproducibility of chromatographic data. Flow distributors and frits can introduce serious band broadening when separation is performed in short, narrow-bore columns. The kinetic performances of packed and monolithic columns are usually similar for well-retained analytes. However, monolithic columns may show significantly better performance for early-eluting compounds, which can be attributed to the moderate mobile phase dispersion caused by the simpler column hardware because no frits are required.