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High-Throughput Analysis of Volatile Impurities in Sustainable Packaging using SIFT-MS Automated Sample Prep in Regulated and Nonregulated Labs Just Got Easier Trends in Modern LC Separation Workflows Strongly Adsorbing Analytes: What, Why, and How to Fix It What Are Employers Looking For When Hiring Separation Scientists?

High-Throughput Analysis of Volatile Impurities in Sustainable Packaging using SIFT-MSAutomated Sample Prep in Regulated and Nonregulated Labs Just Got EasierTrends in Modern LC Separation WorkflowsStrongly Adsorbing Analytes: What, Why, and How to Fix ItWhat Are Employers Looking For When Hiring Separation Scientists?

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View More Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample Preparation Mass Spectrometry Pharmaceutical Analysis Environmental Analysis Food and Beverage Analysis

Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample PreparationMass SpectrometryPharmaceutical AnalysisEnvironmental AnalysisFood and Beverage Analysis

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All PublicationsLCGC North AmericaLCGC EuropeLCGC Asia PacificLCGC SupplementsThe ColumnE-BooksThe Application Notebook

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All App Notes Biological, Medical, and Clinical Biopharmaceuticals Cannabis Chiral Environmental Food and Beverage GC GC-MS General Industrial LC LC-MS Medical/Biological Misc Techniques Pharmaceuticals Polymers Sample Prep Size-Exclusion Chromatography (SEC)Supercritical Fluid Chromatography (SFC)

All App NotesBiological, Medical, and ClinicalBiopharmaceuticalsCannabisChiralEnvironmentalFood and BeverageGCGC-MSGeneralIndustrialLCLC-MSMedical/BiologicalMisc TechniquesPharmaceuticalsPolymersSample PrepSize-Exclusion Chromatography (SEC)Supercritical Fluid Chromatography (SFC)

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ProductsE-BooksChromTubeEventsAnalytically Speaking PodcastPodcastsPodcast SeriesSponsored VideosQ&AsSponsored ContentContent Engagement HubsTips & TricksIndustry InsightsCareer Opportunities

Charles William Russ IV | Authors

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Why Use Signal-To-Noise As a Measure of MS Performance When It Is Often Meaningless?

Signal-to-noise of a chromatographic peak from a single measurement has been used determine the performance of two different MS systems, but this parameter can no longer be universally applied and often fails to provide meaningful estimates of the instrument detection limits (IDL).