Greg Wells | Authors

Signal-to-noise of a chromatographic peak from a single measurement has been used determine the performance of two different MS systems, but this parameter can no longer be universally applied and often fails to provide meaningful estimates of the instrument detection limits (IDL).

Today's ion traps use advanced scanning techniques such as automatic gain control, axial modulation, and triple resonance scanning, resulting in efficient control of both ionization and optimal storage of ions in the trap during analysis. These instruments provide excellent sensitivity and quantitative data, even in "dirty" samples.