Danilo Sciarrone

On-line heart-cut LC–GC and, more recently, comprehensive LC–GC (LC?GC) are very powerful analytical techniques because of the combination of the selectivity features of LC with the high efficiency of GC. This article presents an overview of the most recently used interfacing systems, as well as applications in the food analysis.

The analysis of tea tree oil requires a severe quality control due to its potential to induce and elicit skin allergies. Tea tree oil is an essential oil and consists of a large number of constituents. Heart-cut Multidimensional GC–MS is very well suited to analysis of samples of such high complexity.

A total of fourteen cuts were defined because the retention time difference between several skin sensitizors was only slight.