Analyzing representative standard mixtures, APIs, and synthetic impurities shows that when TRLC is combined with RPLC in 2D-LC, separation performance is improved. We explain why.
Jonas Veenhoven
Advertisement
Jonas Veenhoven is with the Separation Science Group at Ghent University, in Ghent, Belgium.
Articles by Jonas Veenhoven
In this first TRLC instalment, our recent developments, new possibilities, and current limitations of the use of 1D TRLC are discussed, while the column performance is described with respect to the fundamentals of HPLC.
TRLC can obtain separations similar to those of reversed-phase LC while using only water as the mobile phase.
Advertisement
Latest Updated Articles
Perspectives in Hydrophobic Interaction Temperature-Responsive Liquid ChromatographyPublished: February 1st 2023 | Updated:
Possibilities and Limitations of Aqueous Temperature Responsive Liquid Chromatography in Comprehensive 2D–LCPublished: August 2nd 2023 | Updated:
Perspectives in Hydrophobic Interaction Temperature- Responsive Liquid Chromatography (TRLC)Published: December 1st 2022 | Updated:
Advertisement
Advertisement
Trending on LCGC International
1
Navigating Adverse Reactions in GLP-1 Treatment
2
Decoding Sweet Potato Drought Resilience: Metabolomic Evidence from UPLC-MS Profiling
3
Toward Safer Diabetes Devices: GC–MS Detection of Allergens in Sensors, Pumps, and Infusion Sets
4
Shifting GLP-1 Receptor Agonists from Proteins to Small Molecules
5
