Jonathan G. Shackman | Authors

With modern chromatography modeling software, is it time to hang up our laboratory coats? Is resistance to software solving separations futile?

HILIC has rapidly evolved into a practical technique. For analyzing highly polar compounds, HILIC can be far more straightforward than GC or reversed-phase LC with derivatization, and can lead to a simpler final method with robustness comparable to that of reversed-phase LC.