If you are analyzing metal-sensitive biomolecules, and a bioinert instrument is unavailable, or insufficient, passivation or mobile-phase additives may help. Here’s how to use those solutions, with tips for avoiding potential pitfalls.
Oscar G. Potter
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Articles by Oscar G. Potter
Bioinert and biocompatible liquid chromatography (LC) systems are becoming more commonplace in laboratories, but the majority of biomolecule separations still use LC systems composed primarily of stainless steel parts. Can passivation or mobile phase additives improve separations on these systems for metal-sensitive biomolecules?
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Troubleshooting LC Separations of Biomolecules, Part 2: Passivation and Mobile-Phase AdditivesPublished: July 31st 2020 | Updated:
Troubleshooting LC Separations of Biomolecules, Part II: Passivation and Mobile-Phase AdditivesPublished: August 1st 2020 | Updated:
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