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Biopharmaceutical Perspectives
Biopharmaceuticals and Protein Analysis
Cannabis Analysis
Capillary Electrophoresis
Chiral Chromatography
ChromAcademy
Corporate Profiles
Data Acquisition, Handling, and Archiving
Data Analysis, Statistics, and Chemometrics
Dietary Supplements Analysis
Environmental Analysis
Field-Flow Fractionation (FFF)
Food and Beverage Analysis
Forensics, Narcotics
From the Editor
GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
LCGC TV: Gas Chromatography
LCGC TV: Hyphenated Techniques
LCGC TV: Liquid Chromatography
LCGC TV: Sample Preparation
LC–MS
Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
Pharmaceutical Analysis
Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
The Next Generation
Thin Layer Chromatography
Trends
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Gregory O. Staples

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Articles

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Troubleshooting LC Separations of Biomolecules, Part II: Passivation and Mobile-Phase Additives

Troubleshooting LC Separations of Biomolecules, Part II: Passivation and Mobile-Phase Additives

Jordy J. Hsiao;Te-Wei Chu;Oscar G. Potter;Gregory O. Staples;Dwight R. Stoll
August 1st 2020

If you are analyzing metal-sensitive biomolecules, and a bioinert instrument is unavailable, or insufficient, passivation or mobile-phase additives may help. Here’s how to use those solutions, with tips for avoiding potential pitfalls.

Troubleshooting LC Separations of Biomolecules, Part I: Background, and the Meaning of Inertness

Troubleshooting LC Separations of Biomolecules, Part I: Background, and the Meaning of Inertness

Dwight R. Stoll;Jordy J. Hsiao;Gregory O. Staples
March 1st 2020

How do I know when bioinert liquid chromatography columns, systems, or components are needed for my separations of biomolecules?

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