PerkinElmer, Inc.

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP

USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System

Efficient and compliant HPLC analysis of pregabalin

Determination of four complex carbohydrates utilizing a PerkinElmer LC 300 HPLC System, a hydrophilic interaction chromatography (HILIC) technique

HPLC method for saccharide content determination via method CRA SACCH.03 through the analysis of nine commercially available high fructose corn syrups

Determination of 16 common cannabinoids utilizing a PerkinElmer LC 300 HPLC System

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs

USP-compliant method for determination of six isoflavone compounds in dietary supplement capsules with the PerkinElmer LC 300 UHPLC System with PDA detector

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

Per- and polyfluoroalkyl substances (PFAS) are of increasing concern. In October 2021, the U.S. Environmental Protection Agency (EPA) announced an action plan for addressing PFAS, including establishing maximum contaminant levels for drinking water. The vast presence and detrimental impact to human health and the environment of these analytically challenging compounds has led to focus on technique rigor necessary for sensitive, reproduceable and reliable data. In this podcast, Senior Application Scientist, Jamie Foss, addresses the differences between EPA methods 533 and 537.1, and how to overcome key LC-MS/MS technique challenges when performing analysis in accordance with these methods.

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs .

A variety of C18-type columns are evaluated for the identification of levetiracetam via the USP monograph.

Symmetrical, well-resolved peaks easily meet USP performance requirements for the analysis of levetiracetam impurities.

Symmetrical, well-resolved peaks easily meet USP performance requirements for the analysis of pramipexole dihydrochloride.

Easily meet USP method requirements with reduced backpressure using a larger ID column.

A variety of C18-type columns are evaluated for the identification of hydrocortisone via the USP monograph.

Looking to switch LC columns for pharmaceutical drug applications? Method transfer from Luna columns is made seamless with the targeted selectivity of Sonoma LC columns.

A quick reference chart explaining allowable changes to isocratic and gradient HPLC methods

Symmetrical, well-resolved peaks easily meet USP performance requirements for the analysis of fluconazole.

Custodion® Coiled Microextraction syringes and the Torion® T- 9 Portable GC–MS are fast, easy-to-use screening tools for drugs of abuse and new psychoactive substances.

This validation study demonstrates the use of the QSight® tandem quadrupole mass spectrometer (LC–MS/MS) for the application of PFAS EPA Method 537.1 in drinking water.

In this application note, an HPLC with MWD detection method is detailed to detect parabens in cosmetic and personal care products.

This application note details two LC–MS/MS methods for the analysis of 30 analytes from veterinary drugs in milk.

A simple, fast, robust green chemistry method for the accurate quantitation of six additives in diet soft drinks using HPLC with photodiode array (PDA) detection.

This application note highlights the use of solid-phase extraction (SPE) coupled with LC–MS/MS for sample enrichment and quantitation of endocrine-disrupting chemicals.

This application note describes a rapid LC–MS/MS method for the separation and detection of 44 drug of abuse compounds in urine samples.