Per- and polyfluoroalkyl substances (PFAS) are of increasing concern. In October 2021, the U.S. Environmental Protection Agency (EPA) announced an action plan for addressing PFAS, including establishing maximum contaminant levels for drinking water. The vast presence and detrimental impact to human health and the environment of these analytically challenging compounds has led to focus on technique rigor necessary for sensitive, reproduceable and reliable data. In this podcast, Senior Application Scientist, Jamie Foss, addresses the differences between EPA methods 533 and 537.1, and how to overcome key LC-MS/MS technique challenges when performing analysis in accordance with these methods.
Kirstine Nielsen of Aarhus University (Denmark) discusses how targeted metabolomics ratios helped build a robust bloodstain time-since-deposition tool.
Gérard Hopfgartner explains how atmospheric pressure photoionization can generate radical cations in LC–MS, unlocking EI-style spectra and NIST's spectral library.
LCGC International spoke to Akina Nara of Japan’s Tohoku Medical and Pharmaceutical University about a new study which links a blood compound to how long a body has been dead.
A method coupling gas chromatography-tandem mass spectrometry (GC-MS/MS) and multiple reaction monitoring (MRM) tracks lipid markers of decomposition in commingled remains.
This week's top stories on the Chromatography Online website spotlight LCGC International's new SFC-focused interview series charting the technique's rise alongside LC and GC, complemented by a practical GC data-reporting refresher and a study using chromatography to detect trace pesticides in tap water.