Integrated Solid-Phase Enzymatic Digestion and Porous Graphitic Carbon Chromatography for Rapid LC–MS Analysis of RNA Modifications
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A research study recently introduced a streamlined, chromatography-compatible workflow for the rapid analysis of RNA modifications by integrating solid-phase enzymatic digestion with downstream liquid chromatography–mass spectrometry (LC–MS). LCGC International spoke to Yixuan (Axe) Xie, an assistant professor at Fudan University (Shanghai, China) and one of the authors of a paper resulting from this study.