Column: The Essentials

Columns

Articles

Glycosylation is the most common monoclonal antibody (mAb) posttranslational modification. What is essential to know about it?

An Introduction to Glycan Analysis

The fundamentals of electron capture detectors, explained.

Electron Capture Detectors

Improved practices in chemistry selection and sample processing may resolve recovery issues related to target analytes or internal standards.

Solving Recovery Problems in Solid-Phase Extraction

We provide a succinct explanation of electron ionization for GC–MS and
illustrate the fundamentals of ion formation.

Electron Ionization in GC–MS

The elution mechanisms for gradient and isocratic HPLC are fundamentally different from each other. Here is what you should understand about both.

Essential Theory of HPLC

 is Group Technical Director of Crawford Scientific Group and CHROMacademy. His background is in pharmaceutical R&D and polymer chemistry, but he has spent the past 20 years in training and consulting, working with Crawford Scientific Group clients to ensure they attain the very best analytical science possible. He has trained and consulted with thousands of analytical chemists globally and is passionate about professional development in separation science, developing CHROMacademy as a means to provide high-quality online education to analytical chemists. His current research interests include HPLC column selectivity codification, advanced automated sample preparation, and LC–MS and GC–MS for materials characterization, especially in the field of extractables and leachables analysis.

Why the technique is a handy component of any analyst’s arsenal.

LC–MS Peptide Mapping: Where to Start and What It Can Tell Us

With autosamplers, we need to be extra careful to avoid contamination.