Incognito found a 2D LC solution to a tricky separation problem but this technique did not meet the client's requirements. The magnanimous columnist admits to a rare defeat on this occasion but praises the thrill of seeking a solution to a perplexing method development problem. Could any readers suggest a more straightforward solution?
Tablets found aboard an ancient shipwreck could identify the early beginnings of medicine. A team of scientists led by Erika Ribechini of the University of Pisa (Pisa, Italy) determined the composition of tablets found aboard a ship-wrecked off the coast of Tuscany (Italy) around 2,000 years ago.1
This article describes the extraction of drug residues by QuEChERS (quick, easy, cheap, effective, rugged and safe) and analysis by liquid chromatography-electrospray ionization?tandem mass spectrometry (LC-ESI?MS?MS), using dynamic multiple reaction monitoring (DMRM), for the improved quantification of veterinary drugs.