Trapping versus Fractionation
When discussing optimization and improvements to costly and time-consuming purification processes "trapping" columns can be an alternative to fractionation.
When discussing optimization and improvements to costly and time‑consuming purification processes “trapping” columns can be an alternative to fractionation. However, when trapping, the compound has to be recovered from the column and transferred into its powder form. This requires consideration of chemical properties, as well as technical realization. This article demonstrates this complexity based on examples of the flow schemes and the software workflow.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
