
The Column
Solid-phase microextraction (SPME) coupled with comprehensive two-dimensional gas chromatography and time-of-flight mass spectrometry (GC×GC–TOF-MS) can be used to detect trace-level fungicides and compounds responsible for undesirable attributes known as “organoleptic faults” in wine. Of particular interest is the analysis of trace-level fungicides, which are difficult to detect using conventional quadrupole GC–MS techniques without resorting to selected ion monitoring mode.






