The Column-07-08-2016

Click the title above to open The Column July 08, 2016 Europe & Asia issue, Volume 12, Number 12, in an interactive PDF format.

Click the title above to open The Column July 08, 2016 North American issue, Volume 12, Number 12, in an interactive PDF format.

News
The Column

July 01, 2016

Eurofins Lancaster Laboratories, a part of Eurofins Scientific, has announced the expansion of its Dungarvan campus. The expansion includes a new building and an expansion of existing facilities.

The Column

Water contamination has come to the forefront of global debate as a result of high profile cases such as those in Flint, Michigan, USA, or the pollution of the Ganges River in India. Koji Kosaka of the National Institute of Public Health, Japan, has investigated the contamination of the Yodo River Basin in Japan, with the precursors of the carcinogen N-Nitrosodimethylamine (NDMA). He recently spoke with The Column about his use of high performance liquid chromatography (HPLC) to uncover the source of contamination and the chemical precursors responsible.

The winners of the 2016 Thermo Scientific Tandem Mass Tag (TMT) Research Award were celebrated at a ceremony held at the 64th American Society of Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Allied Topics in San Antonio, Texas, USA.

Liquid chromatography coupled to tandem mass spectrometry alongside gas chromatography tandem mass spectrometry has been used to analyze 200 pesticides and pesticide metabolites in honeybees.

Mass spectrometry (MS) is emerging as a critical tool in biopharmaceutical late stage development, manufacturing, and quality control (QC) environments. The rapid growth of biologics in development, the increasing demand for more robust analytical technologies to directly monitor the critical quality attributes (CQAs) of these new drugs, and longer term industry initiatives aimed at improving quality and productivity, such as quality by design (QbD) regulatory submissions and continuous manufacturing, are all fueling a greater need for mass monitoring with MS.

News
The Column

July 01, 2016

Postnova Analytics has opened a dedicated office to enhance local support for its UK customers.

The quantitative performance of the latest generation of high-resolution instruments is comparable to that of a triple quadrupole MS, even though different scanning modes are used. Higher-resolution instrumentation also allows flexibility concerning compound identification because the experiment can be set up for targeted quantitation, screening, or both. In an Orbitrap-based instrument, the parallel reaction monitoring (PRM) mode performs most closely to a triple quadrupole mass analyzer using selected reaction monitoring (SRM) mode. This study looks at the performance of an Orbitrap-based LC–MS method for EPA Method 539.

A preview of the upcoming 31st International Symposium on Chromatography (ISC 2016), which will be held 28 August–1 September at University College Cork, Ireland.