The Column-10-04-2012

Protein/peptide discovery data obtained from data-dependent experiments have been used to increase the success rate of targeted quantification assays as well as automate method building.

Global warming is a contentious issue, with different groups voicing opposing opinions on if, how and at what rate the warming is occurring. The general consensus is that with increased industrialization, greenhouse gas emissions have also increased, resulting in the formation of a so-called 'greenhouse effect'. The origin of greenhouse gases is therefore of great interest to the scientific community.

GPC/SEC (gel permeation chromatography/size exclusion chromatography) methods generally contain multiple detectors in order to gather more information about the molecular structure of macromolecules.1. Up until now, however, the practice and the impact of detector combination has not been discussed.

Spodoptera littoralis is a destructive caterpillar pest indigenous to tropical and subtropical areas of agriculture that has the potential, if accidentally imported, of becoming a major greenhouse pest in Northern Europe. The UK government agency Defra reports that many populations of the species are already highly pesticide resistant2.

The Column spoke to Dr J-F Focant, associate professor at the chemistry department of the University of Liege, Belgium, about thenatochemistry and his recently published articles profiling the 'smell of death'.

Conditions of acute and chronic anaemia that are the result of either a long-standing medical condition (sickle-cell anaemia) or surgical intervention (chemotherapy) often require the administration of blood transfusions to improve the capacity of the patient's red blood cells to carry oxygen1. Red blood cell (RBC) populations have a short shelf life in storage as a result of biomechanical and biochemical changes that reduce the RBC functionality. This has an impact on the viability and therapeutic benefits of ex vivo RBC transfusions.

A market profile of Chromatography Data Systems (CDS's) using data extracted and adapted from SDi's recently published Market Analysis and Perspective (MAP) report titled High Performance Liquid Chromatography: Competing Techniques Setting the Bar Higher.