The Column-10-31-2013

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Silicone Protheses for Biomonitoring POPs in Humans

Bethany Degg
October 31st 2013
ArticleNews

Discarded silicone explants, a waste material from the cosmetic surgery industry, could be a new source of sample material for studying POP accumulation in humans.

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Characterization of Styrene-Butadianoene Rubbers by SEC–MALS and AF4–MALS

Stepan Podzimek
October 31st 2013
ArticleArticle

Two samples of styrene-butadianoene rubbers (SBR) were analyzed by SEC and AF4 coupled with a MALS detector.

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Investigating the Molecular Weight and Structure of Linear and Cross-Linked Hyaluronic Acid by SEC-MALS and SEC-Triple Detection

Bassem Sabagh;Agata Papa
October 31st 2013
ArticleArticle

This article demonstrates the application of a MALS detector within a triple detector array to measure absolute molecular weight distribution of hyaluronic acid.

Slipping Up the Career Ladder

Slipping Up the Career Ladder

October 31st 2013
ArticleFeature

Incognito investigates if chromatographers should become scientists or managers to advance their careers.

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Optimizing Gel Permeation Chromatography for Analyzing Polymers used as Drug Excipients

Matt Trass;Sky Countryman;Michael McGinley
October 31st 2013
ArticleArticle

Although gel permeation chromatography (GPC) is not as widely used as other chromatography methods, it continues to be a useful technique for analyzing the size and solution characteristics of organic polymers. In this study, GPC was applied to analyze different polar polymers that are commonly used in drug excipients. As a result of their polarity, some specialized operating conditions were required. Optimizing the separation brought to light many of the common parameters involved in optimizing GPC separations, and those are discussed in detail here.