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Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
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Supercritical Fluid Extraction (SFC)
The Next Generation
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Trends
UHPLC
Web of Science
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June 2023

home / journals / lcgc-europe / june-2023

Approaches to Accelerate LC Method Development in the Laboratory Using Chemometrics and Machine Learning

Approaches to Accelerate LC Method Development in the Laboratory Using Chemometrics and Machine Learning

Gerben B. van Henten;Tijmen S. Bos;Bob W. J. Pirok
June 1st 2023
Peer Reviewed

This review examines different workflows that have been designed and used to facilitate and/or automate method development in liquid chromatography (LC).


High performance liquid chromatography HPLC | Image Credit: © Sophie - stock.adobe.com

What Are Options to Improve My Separation? Part 3: Options to Consider to Improve Resolution of Complex Mixtures

Dwight R. Stoll
June 1st 2023
Events

Building up knowledge of how different factors affect resolving power from a theoretical point of view, as well as what changes are possible within practical constraints, is powerful when we are confronted with a separation that needs to be improved, or when an existing separation is not performing as expected.


Chromatographic columns for HPLC, chemical separation | Image Credit: © Emre - stock.adobe.com

Methods for the Passivation of High Performance LC Instruments and Columns

Diego A. Lopez;Jesse Bischof
June 1st 2023
Events

Nonspecific adsorption leads to poor peak shapes and poor performance from HPLC systems, but coating-enabling technologies can serve as a potential solution. We explain how.


High-performance liquid chromatography equipment, HPLC, in a scientific chemical manufacturing laboratory with electronic machines in research laboratory for diagnostic and analysis of diseases | Image Credit: © Mnica - stock.adobe.com

Functional Copolymers Analysis Using Liquid Chromatography—Sort It Out

Ron A.H. Peters
June 1st 2023
Article

The latest developments and challenges of using liquid chromatography (LC) for copolymer analysis are discussed.

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