LCGC Europe-02-01-2019

Click the title above to open the LCGC Europe February 2019 regular issue, Vol 32, No 02, in an interactive PDF format.

This review article will give a general overview of the liquid chromatographic (LC) and gas chromatographic (GC) methods used by analytical laboratories for the detection and characterization of suspected illegal medicines and health products, including lifesaving drugs (antimicrobials and antimalarials), lifestyle drugs (erectile dysfunction drugs), and biotechnology drugs (doping peptides and skin-tanning peptides). Literature published from 2015 until early 2019 will be surveyed.

LCGC Europe spoke to Yong Liu and Adam Socia from MSD about the cost-saving benefits of implementing green chromatography in the pharmaceutical sector, the importance of analytical method volume intensity (AMVI), and effective practices to reduce solvent consumption and replace harmful solvents, including supercritical fluid chromatography (SFC), fast chromatography, and “cocktail chromatography”.

When can we use completely aqueous eluents with reversed-phase stationary phases, and what happens if we make a mistake?

This instalment of “GC Connections” begins with a brief introduction to GC×GC, follows with examples of how GC×GC opens additional avenues of analysis, and it concludes with information about how to learn more.

Tips to improve signal-to-noise ratio when using standard gas chromatography (GC) equipment.

The third meeting in the “Emerging Separations Technologies” series will take place on Thursday 28 March 2019 at RSC Burlington House, Piccadilly, London.