LCGC Europe-05-01-2006

Testing helps you identify the soft spots in the method, select the best conditions for operation and develop troubleshooting strategies to correct problems when they do occur.

The best parts of the GAMP laboratory system GPG are the life cycle models for both development and implementation of computerized laboratory systems.

This article looks at current practices in bioanalytical chemistry by examining and critically assessing the various parameters that can be altered to achieve high-speed results with high resolution in LC–MS applications. The decision to opt for gradient or isocratic elution is also discussed.

Liquid–liquid extraction (LLE) is among the most widely used sample preparation methods. In this month's instalment of "Sample Preparation Perspectives," Ron Majors discusses newer LLE approaches that offer significant advantages over classic methods. The miniaturization of LLE has resulted in solvent and time savings, improved automation possibilities and faster sample preparation. The techniques of single-drop microextraction, extraction in levitated droplets, flow injection-, membrane-based- and solid-supported extractions are reviewed. Often, these techniques use the same immiscible solvent pairs of conventional LLE.

Any wine can suffer from that corked wine taint. This spoilage, recognized by a distinct aroma of damp musty leaves and a damp cardboard taste, makes a wine undrinkable.

VICAM, the food safety technology business, headquartered in Watertown, Massachusetts, USA, has been acquired by Waters. The deal also included the associated net assets of VICAM and has proceeded under undisclosed terms.