LCGC Europe-08-01-2019

LCGC Europe

Vol 32 No 8 LCGC Europe August 2019 Regular Issue PDF

August 01, 2019

Issue PDF

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Click the title above to open the LCGC Europe August 2019 regular issue, Volume 32, Number 8, in an interactive PDF format.

Development of Fully Automated Bubble-in-Drop Microextraction–Gas Chromatography–Mass Spectrometry of Organochlorine Pesticides in Environmental Waters

August 01, 2019

Cover Story

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In this study, the intentional incorporation of an air bubble into a solvent droplet is proposed for fully automated bubble-in-drop microextraction–gas chromatography–mass spectrometric (BID-GC–MS) analysis of selected organochlorine pesticides as model analytes.

Sizing Up Size-Exclusion Chromatography

August 01, 2019

Features

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André Striegel spoke to LCGC Europe about innovations in size-exclusion chromatography (SEC) in polymer analysis, including the benefits of hyphenating SEC with on-line multi-angle static light scattering (MALS) and differential refractometry (DRI) detection, the non-trivial nature of a “trivial” solution, the complementary value of “interaction” polymer liquid chromatography (LC) techniques, and the role of quintuple detection in practice.

Pass the Salt: Evolution of Coupling Ion-Exchange Separations and Mass Spectrometry

August 01, 2019

LC Troubleshooting

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Direct coupling of ion-exchange separations to mass spectrometric (MS) detection is increasingly being used for analyses of molecules ranging from organic acids to proteins. These approaches leverage both the exquisite selectivity of the ion-exchange mode for charge-based separation, and the tremendous power of mass spectrometry for identification of unknowns and trace-level quantitation.

Modern HPLC Pumps: Perspectives, Principles, and Practices

August 01, 2019

Perspectives in Modern HPLC

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This instalment is the first of a series of four white papers on high performance liquid chromatography (HPLC) modules (pump, autosampler, UV detector, and chromatography data system) to be published in 2019. This instalment provides an overview for analytical-scale HPLC pumps, including their requirements, modern designs, operating principles, trends, and best practices for trouble-free operation.